Lactic acidosis associated with standard dose linezolid in a kidney recipient with impaired renal function

Severe lactic acidosis, a mitochondrial toxicity caused by the recommended standard dosage of linezolid (LZD), may occur in patients with impaired renal function. We describe an adult male who underwent kidney transplantation with stably impaired renal function, severe dyspnea, and abdominal discomf...

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Bibliographic Details
Published in:	The Brazilian journal of infectious diseases Vol. 26; no. 1; p. 101701
Main Authors:	Chen, Chien-Chou, Liu, Wei-Ting, Lin, Shih-Hua
Format:	Journal Article
Language:	English
Published:	Brazil Elsevier España, S.L.U 01-01-2022 Contexto Elsevier Brazilian Society of Infectious Diseases
Subjects:	Acidosis, Lactic - chemically induced Acidosis, Lactic - diagnosis Adult Case Report Case studies Chronic kidney disease Complications and side effects Dosage and administration Drug therapy Humans INFECTIOUS DISEASES Kidney - physiology Kidney failure Kidneys Lactic acidosis Linezolid Linezolid - adverse effects Male Organ transplant recipients Risk factors Transplantation Taiwan Linezolid eGFR NTM LZD Chronic kidney disease TDM Lactic acidosis CKD
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