Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall

Giardia passes through two stages during its life cycle, the trophozoite and the cyst. Cyst formation involves the synthesis of cyst wall proteins (CWPs) and the transport of CWPs into encystation-specific vesicles (ESVs). Active vesicular trafficking is essential for encystation, but the molecular...

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Bibliographic Details
Published in:	PLoS neglected tropical diseases Vol. 4; no. 6; p. e697
Main Authors:	Castillo-Romero, Araceli, Leon-Avila, Gloria, Wang, Ching C, Perez Rangel, Armando, Camacho Nuez, Minerva, Garcia Tovar, Carlos, Ayala-Sumuano, Jorge Tonatiuh, Luna-Arias, Juan Pedro, Hernandez, Jose Manuel
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01-06-2010 Public Library of Science (PLoS)
Subjects:	Actins - metabolism Animals Bridged Bicyclo Compounds, Heterocyclic - metabolism Cell Biology/Cell Adhesion Cell Biology/Cell Growth and Division Cell Biology/Chemical Biology of the Cell Cell Biology/Cytoskeleton Cell Biology/Gene Expression Cell Biology/Morphogenesis and Cell Biology Chemical Biology/Protein Chemistry and Proteomics Chemistry/Biochemistry Colleges & universities Cysts Cytoplasmic Vesicles - metabolism Cytoskeleton Gastroenterology and Hepatology/Gastrointestinal Infections Giardia lamblia Giardia lamblia - cytology Giardia lamblia - growth & development Giardia lamblia - metabolism Giardia lamblia - physiology Immunoblotting Immunology/Antigen Processing and Recognition Immunology/Immune Response Infectious Diseases/Protozoal Infections Life Cycle Stages Microbiology/Immunity to Infections Microbiology/Parasitology Microscopy Microscopy, Electron, Scanning Microscopy, Fluorescence Molecular Biology/mRNA Stability Parasites Proteins Protozoan Proteins - genetics Protozoan Proteins - metabolism rab GTP-Binding Proteins - genetics rab GTP-Binding Proteins - metabolism RNA, Catalytic Thiazolidines - metabolism Tropical diseases Up-Regulation Up-Regulation Microscopy, Electron, Scanning Actins Immunoblotting Cytoplasmic Vesicles Protozoan Proteins Bicyclo Compounds, Heterocyclic Life Cycle Stages RNA, Catalytic Giardia lamblia Animals Thiazolidines Cytoskeleton rab GTP-Binding Proteins Microscopy, Fluorescence
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