Increased amoxicillin-clavulanic acid resistance in Escherichia coli blood isolates, Spain

• Published in: Emerging infectious diseases Vol. 14; no. 8; pp. 1259 - 1262
• Main Authors: Oteo, Jesús, Campos, José, Lázaro, Edurne, Cuevas, Oscar, García-Cobos, Silvia, Pérez-Vázquez, María, de Abajo, F J
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-08-2008; Centers for Disease Control and Prevention
• Subjects: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination - pharmacology; amoxicillin–clavulanic acid; Anti-Bacterial Agents - pharmacology; antibiotic resistance; Bacteremia - epidemiology; Bacteremia - microbiology; Control; Dispatch; Dosage and administration; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli - drug effects; Escherichia coli Infections - blood; Escherichia coli Infections - epidemiology; Escherichia coli Infections - microbiology; Female; Genetic aspects; Health aspects; Humans; Identification and classification; Male; Middle Aged; Odds Ratio; Risk Factors; sepsis; Spain; Spain - epidemiology; Spain
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid1408.071059

To determine the evolution and trends of amoxicillin-clavulanic acid resistance among Escherichia coli isolates in Spain, we tested 9,090 blood isolates from 42 Spanish hospitals and compared resistance with trends in outpatient consumption. These isolates were collected by Spanish hospitals that participated in the European Antimicrobial Resistance Surveillance System network from April 2003 through December 2006.