Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin

Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin, which are biosynthetic intermediates from β-carotene to astaxanthin, were investigated. Both adonirubin and adonixanthin showed almost the same activities for inhibition of lipid peroxidation and q...

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Bibliographic Details
Published in:	Journal of Oleo Science Vol. 62; no. 3; pp. 181 - 186
Main Authors:	Maoka, Takashi, Yasui, Hiroyuki, Ohmori, Aya, Tokuda, Harukuni, Suzuki, Nobutaka, Osawa, Ayako, Shindo, Kazutoshi, Ishibashi, Takashi
Format:	Journal Article
Language:	English
Published:	Japan Japan Oil Chemists' Society 01-03-2013 Japan Science and Technology Agency
Subjects:	9,10-Dimethyl-1,2-benzanthracene - antagonists & inhibitors adonirubin adonixanthin Animals anti-carcinogenic activity anti-oxidative activity anti-tumor-promoting activity Anticarcinogenic Agents - chemistry Anticarcinogenic Agents - metabolism Anticarcinogenic Agents - pharmacology Antineoplastic Agents - chemistry Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology Antioxidants - chemistry Antioxidants - metabolism Antioxidants - pharmacology Canthaxanthin - analogs & derivatives Canthaxanthin - biosynthesis Canthaxanthin - chemistry Canthaxanthin - pharmacology Carotenoids - biosynthesis Carotenoids - chemistry Carotenoids - pharmacology Cell Line, Tumor Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Female Humans Lipid Peroxidation - drug effects Mice Mice, Inbred ICR Molecular Structure Paracoccus - chemistry Paracoccus - metabolism Singlet Oxygen - chemistry Skin Neoplasms - chemically induced Skin Neoplasms - drug therapy Structure-Activity Relationship Tetradecanoylphorbol Acetate - antagonists & inhibitors Viral Matrix Proteins - antagonists & inhibitors
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