A genome-wide association study in multiple system atrophy

OBJECTIVE:To identify genetic variants that play a role in the pathogenesis of multiple system atrophy (MSA), we undertook a genome-wide association study (GWAS). METHODS:We performed a GWAS with >5 million genotyped and imputed single nucleotide polymorphisms (SNPs) in 918 patients with MSA of E...

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Bibliographic Details
Published in:	Neurology Vol. 87; no. 15; pp. 1591 - 1598
Main Authors:	Sailer, Anna, Scholz, Sonja W, Nalls, Michael A, Schulte, Claudia, Federoff, Monica, Price, T Ryan, Lees, Andrew, Ross, Owen A, Dickson, Dennis W, Mok, Kin, Mencacci, Niccolo E, Schottlaender, Lucia, Chelban, Viorica, Ling, Helen, OʼSullivan, Sean S, Wood, Nicholas W, Traynor, Bryan J, Ferrucci, Luigi, Federoff, Howard J, Mhyre, Timothy R, Morris, Huw R, Deuschl, Günther, Quinn, Niall, Widner, Hakan, Albanese, Alberto, Infante, Jon, Bhatia, Kailash P, Poewe, Werner, Oertel, Wolfgang, Höglinger, Günter U, Wüllner, Ullrich, Goldwurm, Stefano, Pellecchia, Maria Teresa, Ferreira, Joaquim, Tolosa, Eduardo, Bloem, Bastiaan R, Rascol, Olivier, Meissner, Wassilios G, Hardy, John A, Revesz, Tamas, Holton, Janice L, Gasser, Thomas, Wenning, Gregor K, Singleton, Andrew B, Houlden, Henry
Format:	Journal Article
Language:	English
Published:	United States American Academy of Neurology 11-10-2016 Lippincott Williams & Wilkins
Subjects:	Alkyl and Aryl Transferases - genetics alpha-Synuclein - genetics Brain - metabolism Brain - pathology Clinical Medicine Cohort Studies Europe Genetic Loci Genome-Wide Association Study Genotyping Techniques Humans Klinisk medicin Medical and Health Sciences Medicin och hälsovetenskap Multiple System Atrophy - genetics Multiple System Atrophy - metabolism Multiple System Atrophy - pathology Neurologi Neurology Polymorphism, Single Nucleotide RNA, Messenger - metabolism United States White People - genetics United States Europe
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