特发性黄斑裂孔术中填充物的探讨

目的:探讨如何选择特发性黄斑裂孔术中的填充物。方法:回顾性分析特发性黄斑裂孔手术患者46例46眼的临床资料。A组(23眼)行经睫状体平坦部的三切口玻璃体切除+内界膜剥除+硅油注入术,B组(23眼)行经睫状体平坦部的三切口玻璃体切除+内界膜剥除+C2F6(20%)注入术,术前应用频域光学相干断层扫描及其深度增强成像技术(EDI-OCT)测量黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT)以明确分组。对手术前后最佳矫正视力(best corrected visual acuity,BCVA)、裂孔闭合率、IS/OS破坏直径及手术并发症等进行临床观察。结...

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Published in:国际眼科杂志 Vol. 16; no. 9; pp. 1746 - 1749
Main Author: 许静 冯洁 叶青
Format: Journal Article
Language:Chinese
Published: 272100,中国山东省济宁市第一人民医院眼科 2016
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Summary:目的:探讨如何选择特发性黄斑裂孔术中的填充物。方法:回顾性分析特发性黄斑裂孔手术患者46例46眼的临床资料。A组(23眼)行经睫状体平坦部的三切口玻璃体切除+内界膜剥除+硅油注入术,B组(23眼)行经睫状体平坦部的三切口玻璃体切除+内界膜剥除+C2F6(20%)注入术,术前应用频域光学相干断层扫描及其深度增强成像技术(EDI-OCT)测量黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT)以明确分组。对手术前后最佳矫正视力(best corrected visual acuity,BCVA)、裂孔闭合率、IS/OS破坏直径及手术并发症等进行临床观察。结果:术后随访至少12mo。随访期末A组术后BCVA与术前相比,差异有统计学意义(t=7.659,P〈0.05)。B组术后BCVA与术前相比,差异有统计学意义(t=11.648,P〈0.05)。A组裂孔闭合率100%,B组裂孔闭合率为95.2%。A组术后IS/OS破坏直径与术前相比差异有统计学意义(t=12.252,P〈0.05),B组术后IS/OS破坏直径与术前相比差异有统计学意义(t=13.257,P〈0.05)。并发症:A组术后4眼发生高眼压,B组术后1眼裂孔未闭合继发视网膜脱离,再次行硅油注入术后裂孔闭合。B组术后2眼出现玻璃体积血,1眼吸收,1眼再次行玻璃体腔灌洗术。结论:两种手术方式均可有效治疗特发性黄斑裂孔。A组手术方式可以更持久顶压黄斑区视网膜,利于黄斑裂孔闭合,但是需俯卧较长时间及再次手术取出硅油,增加患者身心和经济负担。B组手术方式无需再次手术取出填充物,但是存在黄斑裂孔不闭合需再次手术的风险。我们将黄斑中心凹下脉络膜厚度作为术前合理选择手术方案的标准,为患者提供个性化的治疗方案。
Bibliography:Jing Xu;Jie Feng;Qing Ye;Department of Ophthalmology,the First People's Hospital of Jining
AIM:To choose the filler for the treatment of idiopathic macular hole(IMH).METHODS:Clinical data of 46 eyes of 46 cases with IMH who underwent surgical treatment were retrospectively analyzed.Patients in Group A(23 eyes) underwent pars plana vitrectomy + membrane peeling + Silicone oil injection and patients in Group B(23 eyes) underwent pars plana vitrectomy + membrane peeling + C2F6(20%)gas liquid injection.EDI-OCT was used to measure the subfoveal choroidal thickness(SFCT) before the surgery.Changes in best corrected visual acuity(BCVA),the closure rate of hole,the damage diameter of IS/OS and the complications after the surgery were observed.RESULTS:The follow-up time was 12 mo at least.In Group A,the post-operative BCVA improved compared with preoperative one and the difference was statistically significant(t = 7.659,P〈0.05).In Group B,the postoperative BCVA improved compared with preoperative one and the difference
ISSN:1672-5123
DOI:10.3980/j.issn.1672-5123.2016.9.40