Effect of Recombinant Surfactant Protein C–Based Surfactant on the Acute Respiratory Distress Syndrome

The acute respiratory distress syndrome (ARDS) results from a deficiency of functional surfactant in the airways. These investigators carried out a multicenter study in which patients with ARDS were treated with a recombinant human surfactant protein C–based surfactant. No clinical benefits were not...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 351; no. 9; pp. 884 - 892
Main Authors:	Spragg, Roger G, Lewis, James F, Walmrath, Hans-Dieter, Johannigman, Jay, Bellingan, Geoff, Laterre, Pierre-Francois, Witte, Michael C, Richards, Guy A, Rippin, Gerd, Rathgeb, Frank, Häfner, Dietrich, Taut, Friedemann J.H, Seeger, Werner
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 26-08-2004
Subjects:	Analysis of Variance APACHE Biological and medical sciences Causality Clinical trials Double-Blind Method Female General aspects Humans Logistic Models Lungs Male Medical sciences Medical treatment Middle Aged Oxygen - blood Pneumology Proteins Pulmonary Surfactant-Associated Protein C - adverse effects Pulmonary Surfactant-Associated Protein C - therapeutic use Pulmonary Surfactants - adverse effects Pulmonary Surfactants - therapeutic use Recombinant Proteins - adverse effects Recombinant Proteins - therapeutic use Respiration, Artificial Respiratory diseases Respiratory Distress Syndrome, Adult - drug therapy Respiratory Distress Syndrome, Adult - etiology Respiratory Distress Syndrome, Adult - mortality Respiratory Distress Syndrome, Adult - therapy Respiratory system : syndromes and miscellaneous diseases Surfactants Survival Rate Treatment Failure Medicine Pulmonary surfactant Respiratory disease Acute Respiratory distress Protein C Recombinant protein Surfactant Syndrome
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