Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice

Mammalian artificial chromosomes derived from native chromosomes have been applied to biomedical research and development by generating cell sources and transchromosomic (Tc) animals. Human artificial chromosome (HAC) is a precedent chromosomal vector which achieved generation of valuable humanized...

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Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; pp. 20050 - 12
Main Authors:	Abe, Satoshi, Honma, Kazuhisa, Okada, Akane, Kazuki, Kanako, Tanaka, Hiroshi, Endo, Takeshi, Morimoto, Kayoko, Moriwaki, Takashi, Hamamichi, Shusei, Nakayama, Yuji, Suzuki, Teruhiko, Takehara, Shoko, Oshimura, Mitsuo, Kazuki, Yasuhiro
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 08-10-2021 Nature Publishing Group Nature Portfolio
Subjects:	631/1647/1511 631/1647/1513 631/1647/2300 631/1647/334 631/208/1405 631/208/212 631/61/17 631/61/212 631/61/2300 631/80/103 Animal models Animals Artificial chromosomes Centromere Centromeres Chromosome 10 Chromosome 11 Chromosomes Chromosomes - genetics Chromosomes, Artificial Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Female Gene Transfer Techniques Genetic Engineering - methods Genetic Vectors - genetics Germ Cells Humanities and Social Sciences Male Medical research Mice Mice, Inbred ICR multidisciplinary Pharmacokinetics R&D Recombination, Genetic Research & development Science Science (multidisciplinary) Zebrafish
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