Magnetic Resonance Imaging of Perfusion Using Spin Inversion of Arterial Water

A technique has been developed for proton magnetic resonance imaging (MRI) of perfusion, using water as a freely diffusable tracer, and its application to the measurement of cerebral blood flow (CBF) in the rat is demonstrated. The method involves labeling the inflowing water proton spins in the art...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 89; no. 1; pp. 212 - 216
Main Authors:	Williams, Donald S., Detre, John A., Leigh, John S., Koretsky, Alan P.
Format:	Journal Article
Language:	English
Published:	Washington, DC National Academy of Sciences of the United States of America 01-01-1992 National Acad Sciences National Academy of Sciences
Subjects:	Animals Biological and medical sciences Biology Blood Blood flow Blood flow velocity Carbon Dioxide - blood Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cerebrovascular Circulation Flow velocity Fundamental and applied biological sciences. Psychology Imaging Magnetic resonance imaging Magnetic Resonance Imaging - methods Magnetization Male Medical imaging Perfusion Perfusion imaging Physics Protons Rats Rats, Inbred Strains Vertebrates: nervous system and sense organs Water - chemistry Water Vertebrata Mammalia Investigation method Rat Imaging Magnetic resonance Rodentia Biological marker Blood flow Brain (vertebrata)
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