Targeting autophagy in cancer

Autophagy is a conserved, self‐degradation system that is critical for maintaining cellular homeostasis during stress conditions. Dysregulated autophagy has implications in health and disease. Specifically, in cancer, autophagy plays a dichotomous role by inhibiting tumor initiation but supporting t...

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Bibliographic Details
Published in:	Cancer Vol. 124; no. 16; pp. 3307 - 3318
Main Authors:	Onorati, Angelique V., Dyczynski, Matheus, Ojha, Rani, Amaravadi, Ravi K.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-08-2018
Subjects:	Autophagy Autophagy - drug effects Autophagy - genetics Cancer Carcinogenesis - drug effects Carcinogenesis - genetics chemotherapy Clinical trials Drug Development Homeostasis Humans Hydroxychloroquine hydroxychloroquine (HCQ) Immunity Immunotherapy Literature reviews Medical research Medicin och hälsovetenskap Molecular Targeted Therapy Neoplasms - drug therapy Neoplasms - epidemiology Neoplasms - genetics Oncology Phagocytosis Tumors hydroxychloroquine (HCQ) Autophagy chemotherapy immunotherapy
Online Access:	Get full text
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