The Diagnosis and Prognosis of Autosomal Dominant Polycystic Kidney Disease

AUTOSOMAL dominant polycystic kidney disease is responsible for 6 to 9 percent of cases of end-stage renal disease in North America 1 ' 2 and Europe. 3 About 1 in 1000 persons carries a mutant gene for this condition. 4 The disease can be diagnosed before symptoms develop by ultrasonographic im...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 323; no. 16; pp. 1085 - 1090
Main Authors:	Parfrey, Patrick S, Bear, John C, Morgan, Janet, Cramer, Benvon C, McManamon, Patrick J, Gault, Mathew H, Churchill, David N, Singh, Manoj, Hewitt, Richard, Somlo, Stefan, Reeders, Stephen T
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 18-10-1990
Subjects:	Adult Age Biological and medical sciences Chromosome 16 Chromosomes, Human, Pair 16 Confidence intervals Cysts Diagnosis End-stage renal disease Epidemiology Genes, Dominant Genetic Linkage Genetics Genomes Genotype Genotypes Humans Hypertension Hypertension - etiology Kidney diseases Kidney Diseases - etiology Kidney Failure, Chronic - etiology Medical diagnosis Medical prognosis Medical sciences Middle Aged Mutation Nephrology. Urinary tract diseases Polycystic kidney Polycystic Kidney Diseases - diagnosis Polycystic Kidney Diseases - genetics Polycystic Kidney Diseases - mortality Prognosis Renal failure Sensitivity and Specificity Studies Ultrasonic imaging Ultrasonography Ultrasound Urinary tract diseases Urinary tract infections Urogenital system Renal disease Prognosis Diagnosis Family study Polycystic kidney
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