Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes

Colorectal cancer (CRC) is among the deadliest cancers, wherein early dissemination of tumor cells, and consequently, metastasis formation, are the main causes of mortality and poor prognosis. Cofilin-1 (CFL-1) and its modulators, LIMK1/SSH1, play key roles in mediating the invasiveness by driving a...

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Bibliographic Details
Published in:	Cancer cell international Vol. 21; no. 1; p. 69
Main Authors:	Sousa-Squiavinato, Annie Cristhine Moraes, Vasconcelos, Renata Ivo, Gehren, Adriana Sartorio, Fernandes, Priscila Valverde, de Oliveira, Ivanir Martins, Boroni, Mariana, Morgado-Díaz, Jose Andrés
Format:	Journal Article
Language:	English
Published:	England BioMed Central 22-01-2021 BMC
Subjects:	Actin Antibodies Biomarkers Cancer Cell adhesion & migration Cofilin Cofilin-1 Colorectal cancer Colorectal carcinoma Consensus molecular subtypes Cytoskeleton Gene expression Genomes Immunomodulation Invasiveness Kinases LIM kinase LIMK1 Lymph node metastasis Lymph nodes Lymphatic system Mesenchyme Metastases Metastasis Pathology Patients Phenotypes Primary Research Protein expression Proteins Software SSH1 Tumor cells Tumors United States > US Lymph node metastasis Cofilin-1 Consensus molecular subtypes Colorectal cancer LIMK1 SSH1
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