Chloride channels of intracellular membranes

Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular c...

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Bibliographic Details
Published in:	FEBS letters Vol. 584; no. 10; pp. 2102 - 2111
Main Authors:	Edwards, John C., Kahl, Christina R.
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 17-05-2010
Subjects:	Animals Bestrophin Biological Transport CFTR Chloride channel Chloride Channels - metabolism ClC CLIC cystic fibrosis transmembrane conductance regulator endoplasmic reticulum Golgi pH regulator GPHR Humans Intracellular Membranes - metabolism sarcoplasmic reticulum GPHR Chloride channel ClC Golgi pH regulator CLIC Bestrophin ER CFTR SR
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Summary:	Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0014-5793 1873-3468
DOI:	10.1016/j.febslet.2010.01.037