T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells

The Lck and Src binding adaptor protein TSAd (T cell specific adaptor) regulates actin polymerization in T cells and endothelial cells. The molecular details as to how TSAd regulates this process remain to be elucidated. To identify novel interaction partners for TSAd, we used a scoring matrix-assis...

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Bibliographic Details
Published in:	Cell communication and signaling Vol. 13; no. 1; p. 31
Main Authors:	Hem, Cecilie Dahl, Sundvold-Gjerstad, Vibeke, Granum, Stine, Koll, Lise, Abrahamsen, Greger, Buday, Laszlo, Spurkland, Anne
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 11-07-2015 BioMed Central
Subjects:	Actin Adaptor Proteins, Signal Transducing - analysis Adaptor Proteins, Signal Transducing - metabolism Algorithms Amino Acid Sequence Animals Cells, Cultured HEK293 Cells Humans Jurkat Cells Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - analysis Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - metabolism Mice, Inbred C57BL Molecular Sequence Data Muscle proteins Oncogene Proteins - analysis Oncogene Proteins - metabolism Peptides Phosphoproteins - analysis Phosphoproteins - metabolism Physiological aspects Polymerization Protein binding Protein Interaction Maps src Homology Domains T cells T-Lymphocytes - metabolism Tyrosine
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