EPIDEMIOLOGY OF NEGLECTED TROPICAL DISEASES IN TRANSPLANT RECIPIENTS. REVIEW OF THE LITERATURE AND EXPERIENCE OF A BRAZILIAN HSCT CENTER

• Published in: Revista do Instituto de Medicina Tropical de São Paulo Vol. 51; no. 6; pp. 309 - 324
• Main Authors: MARTINS MACHADO, Clarisse, CHAVES MARTINS, Talita, COLTURATO, Iago, SOUZA LEITE, Marília, SIMIONE, Anderson João, PEDRO DE SOUZA, Mair, MAUAD, Marcos Augusto, RENSI COLTURATO, Vergílio
• Format: Journal Article
• Language: English
• Published: São Paulo Instituto de Medicina Tropical de São Paulo 01-12-2009; Instituto de Medicina Tropical de Sao Paulo; Instituto de Medicina Tropical
• Subjects: Adolescent; Adult; Aged; Biological and medical sciences; Brazil - epidemiology; Child; Child, Preschool; Communicable Diseases - epidemiology; Female; General aspects; Hematopoietic Stem Cell Transplantation - adverse effects; Hematopoietic Stem Cell Transplantation - mortality; Humans; Infant; Infant, Newborn; Male; Medical sciences; Middle Aged; Organ Transplantation - adverse effects; Organ Transplantation - mortality; Organ Transplantation - statistics & numerical data; Retrospective Studies; TROPICAL MEDICINE; Young Adult; South America; Brazil; America; Developing countries; Transplantation; Homotransplantation; Epidemiology; Neglected tropical diseases; Neglected disease; Treatment; Tropical disease; Surgery; Graft; Tropical medicine; HSCT; Bibliographic review
• ISSN: 0036-4665; 1678-9946; 1678-9946; 0036-4665
• DOI: 10.1590/s0036-46652009000600002

The rising success rate of solid organ (SOT) and haematopoietic stem cell transplantation (HSCT) and modern immunosuppression make transplants the first therapeutic option for many diseases affecting a considerable number of people worldwide. Consequently, developing countries have also grown their transplant programs and have started to face the impact of neglected tropical diseases (NTDs) in transplant recipients. We reviewed the literature data on the epidemiology of NTDs with greatest disease burden, which have affected transplant recipients in developing countries or may represent a threat to transplant recipients living in other regions. Tuberculosis, Leprosy, Chagas disease, Malaria, Leishmaniasis, Dengue, Yellow fever and Measles are the topics included in this review. In addition, we retrospectively revised the experience concerning the management of NTDs at the HSCT program of Amaral Carvalho Foundation, a public transplant program of the state of São Paulo, Brazil.