Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy

Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM receptor dystroglycan (Dg). Remarkably, among many cases of diagnosed dystroglycanopathies, only a small fraction can be linked directly to m...

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Bibliographic Details
Published in:	BMC medicine Vol. 18; no. 1; p. 8
Main Authors:	Yatsenko, Andriy S, Kucherenko, Mariya M, Xie, Yuanbin, Aweida, Dina, Urlaub, Henning, Scheibe, Renate J, Cohen, Shenhav, Shcherbata, Halyna R
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 21-01-2020 BioMed Central BMC
Subjects:	Aging Analysis Atrophy Congenital diseases Cytoskeleton Diagnosis Diseases Drosophila Drug development Dystroglycan Dystrophy Enzymes Extracellular matrix Gene expression Genes Genetic aspects Genetic research Hereditary diseases Heterogeneity Hippo kinase signaling Homology Insects Interactomes Intracellular signalling Kibra Kinases Mass spectrometry Mass spectroscopy Medical treatment Muscle degeneration Muscles Muscular atrophy Muscular dystrophy Musculoskeletal system Mutation Myocytes Novels Proteins Proteomics Signal transduction Signaling Spectroscopy Therapeutics Vertebrates Yorkie Germany Dystroglycan Kibra Muscle atrophy Muscle degeneration Proteomics Hippo kinase signaling Muscular dystrophies Yorkie
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