Therapeutic effects of oxaliplatin-based neoadjuvant chemotherapy and chemoradiotherapy in patients with locally advanced rectal cancer: a single-center, retrospective cohort study

Neoadjuvant chemoradiotherapy (NACRT) has now become the standard treatment for locally advanced rectal cancer (LARC). NACRT has decreased local relapse (LR) rate in patients with LARC; however, distant relapse has recently attracted much attention. This study aimed to assess the feasibility and eff...

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Bibliographic Details
Published in:	World journal of surgical oncology Vol. 16; no. 1; pp. 105 - 8
Main Authors:	Okuyama, Takashi, Sameshima, Shinichi, Takeshita, Emiko, Yoshioka, Ryuji, Yamagata, Yukinori, Ono, Yuko, Tagaya, Nobumi, Noie, Tamaki, Oya, Masatoshi
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 05-06-2018 BioMed Central BMC
Subjects:	5-Fluorouracil Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biopsy Cancer Cancer therapies Chemoradiotherapy Chemoradiotherapy - methods Chemoradiotherapy, Adjuvant Chemotherapy Chemotherapy, Adjuvant Cohort analysis Colorectal cancer Combined Modality Therapy Diagnosis Diarrhea Disease-Free Survival Dosage and administration Feasibility studies Female Fluorouracil - administration & dosage Gangrene Humans Laparoscopy Locally advanced rectal cancer Lymph nodes Lymphatic system Male Metastasis Middle Aged Mutation Neoadjuvant chemoradiotherapy Neoadjuvant Therapy Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Neutropenia NMR Nuclear magnetic resonance Oxaliplatin Oxaliplatin - administration & dosage Oxaliplatin - therapeutic use Oxaliplatin-based neoadjuvant chemotherapy Patients Prognosis Radiation therapy Radiotherapy Rectal Neoplasms - drug therapy Rectal Neoplasms - pathology Rectal Neoplasms - surgery Rectum Relapse-free survival Retrospective Studies Surgeons Surgery Survival Systematic review Treatment Outcome Tumors Locally advanced rectal cancer Oxaliplatin-based neoadjuvant chemotherapy Neoadjuvant chemoradiotherapy Relapse-free survival
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