Appetite regulating factors in dourado, Salminus brasiliensis : cDNA cloning and effects of fasting and feeding on gene expression

Highlights • cDNAs for orexin, CART and CCK were isolated in dourado. • Orexin and CCK have widespread mRNA distributions, CART is limited to the brain. • Orexin, but not CART and CCK, expression was affected by fasting. • CART and CCK, but not orexin, displayed periprandial changes.

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Bibliographic Details
Published in:	General and comparative endocrinology Vol. 237; pp. 34 - 42
Main Authors:	Volkoff, Hélène, Sabioni, Rafael Estevan, Cyrino, José Eurico Possebon
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-10-2016
Subjects:	Animals Appetite - physiology CART CCK Characidae - genetics Characidae - physiology Cholecystokinin - genetics Cholecystokinin - metabolism Cloning, Molecular DNA, Complementary - genetics DNA, Complementary - metabolism Endocrinology & Metabolism Fasting Fasting - physiology Feeding Feeding Behavior - physiology Gene Expression Profiling Gene Expression Regulation Hypothalamus - metabolism mRNA expression Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Orexin Orexins - genetics Orexins - metabolism Real-Time Polymerase Chain Reaction RNA, Messenger - genetics Salminus brasiliensis Tissue Distribution USA, California, American R Fasting CCK Salminus brasiliensis Orexin CART Feeding mRNA expression
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Summary:	Highlights • cDNAs for orexin, CART and CCK were isolated in dourado. • Orexin and CCK have widespread mRNA distributions, CART is limited to the brain. • Orexin, but not CART and CCK, expression was affected by fasting. • CART and CCK, but not orexin, displayed periprandial changes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0016-6480 1095-6840
DOI:	10.1016/j.ygcen.2016.07.022