White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

© 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/). Genetic frontotemporal dementia is most commonly caused by mutations in the progranulin (GRN), microtubule-associated protein tau (MAPT) and chromosome...

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Published in:	NeuroImage clinical Vol. 15; pp. 171 - 180
Main Authors:	Sudre, Carole H., Bocchetta, Martina, Cash, David, Thomas, David L., Woollacott, Ione, Dick, Katrina M., van Swieten, John, Borroni, Barbara, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Graff, Caroline, Tagliavini, Fabrizio, Frisoni, Giovanni, Laforce, Robert, Finger, Elizabeth, de Mendonça, Alexandre, Sorbi, Sandro, Ourselin, Sébastien, Cardoso, M. Jorge, Rohrer, Jonathan D., Andersson, Christin, Archetti, Silvana, Arighi, Andrea, Benussi, Luisa, Binetti, Giuliano, Black, Sandra, Cosseddu, Maura, Fallström, Marie, Ferreira, Carlos, Fenoglio, Chiara, Fox, Nick C., Freedman, Morris, Fumagalli, Giorgio, Gazzina, Stefano, Ghidoni, Roberta, Grisoli, Marina, Jelic, Vesna, Jiskoot, Lize, Keren, Ron, Lombardi, Gemma, Maruta, Carolina, Mead, Simon, Meeter, Lieke, van Minkelen, Rick, Nacmias, Benedetta, Öijerstedt, Linn, Padovani, Alessandro, Panman, Jessica, Pievani, Michela, Polito, Cristina, Premi, Enrico, Prioni, Sara, Rademakers, Rosa, Redaelli, Veronica, Rogaeva, Ekaterina, Rossi, Giacomina, Rossor, Martin N., Scarpini, Elio, Tang-Wai, David, Thonberg, Hakan, Tiraboschi, Pietro, Verdelho, Ana, Warren, Jason D.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier 01-01-2017
Subjects:	Adult Aged C9orf72 Protein - genetics Cohort Studies Confidence interval Female Frontotemporal dementia Frontotemporal Dementia - diagnostic imaging Frontotemporal Dementia - genetics Frontotemporal Dementia - pathology FTD Humans Inter Quartile Range Intercellular Signaling Peptides and Proteins - genetics IQR Magnetic Resonance Imaging Male Medicin och hälsovetenskap Medicinsk genetik Medicinska och farmaceutiska grundvetenskaper Middle Aged Neurovetenskaper Presymptomatic Progranulins Regular Symptomatic tau Proteins - genetics TIV Total Intracranial volume White Matter - diagnostic imaging White Matter - pathology White matter hyperintensity WMH PS, Presymptomatic CI, Confidence interval TIV, Total Intracranial volume FTD, Frontotemporal dementia IQR, Inter Quartile Range WMH, White matter hyperintensity S, Symptomatic
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