Protective Actions of Anserine Under Diabetic Conditions

In rodents, carnosine treatment improves diabetic nephropathy, whereas little is known about the role and function of anserine, the methylated form of carnosine. Antioxidant activity was measured by oxygen radical absorbance capacity and oxygen stress response in human renal tubular cells (HK-2) by...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 19; no. 9; p. 2751
Main Authors:	Peters, Verena, Calabrese, Vittorio, Forsberg, Elisabete, Volk, Nadine, Fleming, Thomas, Baelde, Hans, Weigand, Tim, Thiel, Christian, Trovato, Angela, Scuto, Maria, Modafferi, Sergio, Schmitt, Claus Peter
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 13-09-2018 MDPI
Subjects:	Amino acids Animals anserine Anserine - therapeutic use Antioxidants Antioxidants - therapeutic use Carbonyls Carnosine Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - drug therapy Diabetic Nephropathies - drug therapy Diabetic nephropathy Drug dosages Glucose Heat shock proteins Homeostasis Hsp70 Hsp70 protein Human behavior Hydrogen peroxide Hydrogen Peroxide - metabolism Immunoblotting Intracellular Intravenous administration Kidney Tubules - drug effects Kidney Tubules - metabolism Kidneys Male Measurement methods Metabolism Metabolites Mice Mice, Inbred C57BL mRNA Nephropathy Nitrates Permeability Polymerase chain reaction Proteinuria Rodents Thioredoxin vascular permeability Germany Hsp70 carnosine proteinuria anserine vascular permeability diabetes diabetic nephropathy
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