Water Structure in Cubic Insulin Crystals

The electron density distribution of the solvent in the cubic insulin crystal structure, which occupies 65% of the volume, has been mapped from 1.7-$\overset{^\circ}{A}$resolution diffraction data by an iterative difference Fourier method, using the previously determined protein structure as the ref...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 88; no. 2; pp. 622 - 626
Main Authors:	Badger, John, Caspar, D. L. D.
Format:	Journal Article
Language:	English
Published:	Washington, DC National Academy of Sciences of the United States of America 15-01-1991 National Acad Sciences
Subjects:	Arithmetic mean Atoms Biological and medical sciences Crystalline structure Crystals Cubic crystals Density Electron density Fourier Analysis Fundamental and applied biological sciences. Psychology Insulin Insulin - chemistry Models, Molecular Molecular biophysics Molecules Protein Conformation R factors Solvents Structure in molecular biology Water X-Ray Diffraction - methods Water Protein hormone Cubic crystals Electron density map Refinement Method X ray diffraction Insulin Crystalline structure
Online Access:	Get full text
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