A Controlled Study of Serum Lipid Profiles in Indian Patients with Depressive Episode

• Published in: Indian journal of psychological medicine Vol. 36; no. 2; pp. 129 - 133
• Main Authors: Patra, Bichitra Nanda, Khandelwal, Sudhir K., Chadda, Rakesh K., Ramakrishnan, Lakshmy
• Format: Journal Article
• Language: English
• Published: New Delhi, India SAGE Publications 01-04-2014; Sage Publications Ltd. (UK); Sage Publications, New Delhi India; Medknow Publications & Media Pvt Ltd; SAGE Publishing
• Subjects: Blood cholesterol; Body mass-index; depression; Low density lipoproteins; Medical research; Medicine, Experimental; Original; self-harm; serum cholesterol; serum lipid profiles; suicide; Body mass-index; depression; self-harm; serum cholesterol; serum lipid profiles; suicide
• ISSN: 0253-7176; 0975-1564
• DOI: 10.4103/0253-7176.130968

Lower levels of circulating lipid fractions and cholesterol are risk factors for impulsivity and depressive disorder. A lower level of serum cholesterol is also associated with patients presenting with history of self-harm.
A total of 30 depressive patients and 30 healthy matched control subjects were recruited from the department of Psychiatry of a tertiary care hospital. We measured serum total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein cholesterol and triglyceride levels of both patient and control group.
The serum TC and LDL-cholesterol levels were found to be significantly lower in study group than that of control group.
Lower levels of serum cholesterol are associated with depressive disorder.