HLA-Haplotypes Influence Microbiota Structure in Northwestern Mexican Schoolchildren Predisposed for Celiac Disease or Type 1 Diabetes

To contribute to and elucidate the participation of microbiota in celiac disease (CD) and type 1 diabetes (T1D) development, we evaluated the influence of HLA haplotypes, familial risk, and diet on the microbiota of schoolchildren. We conducted a cross-sectional study on 821 apparently healthy schoo...

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Bibliographic Details
Published in:	Microorganisms (Basel) Vol. 11; no. 6; p. 1412
Main Authors:	Aguayo-Patrón, Sandra V, Trujillo-Rivera, Omar A, Cornejo-Granados, Fernanda, Ochoa-Leyva, Adrian, Calderón de la Barca, Ana M
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 27-05-2023 MDPI
Subjects:	Amino acid composition Amino acids Antibiotics Antibodies At risk youth Autoantibodies Autoimmune diseases Autoimmunity Biosynthesis Breastfeeding & lactation Celiac disease Children Children & youth Diabetes mellitus (insulin dependent) Diet Disease Elementary school students Enzyme-linked immunosorbent assay Families & family life Fecal microflora Gene sequencing Genetic aspects Genotyping Guardians Haplotypes Health aspects Health care Health risk assessment Histocompatibility antigen HLA Histocompatibility antigens HLA DQ2 and DQ8 HLA histocompatibility antigens Lachnospiraceae Metabolism Metabolites Methods Microbiota Microbiota (Symbiotic organisms) Microorganisms Northwestern Mexico Parabacteroides Phylogeny Physiological aspects Relative abundance Risk analysis Risk factors RNA sequencing rRNA 16S schoolchildren Sucrose Taxonomy Type 1 diabetes Mexico United States > US microbiota schoolchildren celiac disease type 1 diabetes Northwestern Mexico HLA DQ2 and DQ8
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