Role of genetic heterogeneity in determining the epidemiological severity of H1N1 influenza

Genetic differences contribute to variations in the immune response mounted by different individuals to a pathogen. Such differential response can influence the spread of infectious disease, indicating why such diseases impact some populations more than others. Here, we study the impact of populatio...

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Bibliographic Details
Published in:	PLoS computational biology Vol. 14; no. 3; p. e1006069
Main Authors:	Sambaturu, Narmada, Mukherjee, Sumanta, López-García, Martín, Molina-París, Carmen, Menon, Gautam I, Chandra, Nagasuma
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 21-03-2018 Public Library of Science (PLoS)
Subjects:	Acids Alleles Applied mathematics Bacterial infections Bioinformatics Biology Biology and life sciences Computer Simulation Disease Outbreaks Disease Susceptibility - epidemiology Epidemics Epidemiology Epitopes Ethnicity Ethnicity - genetics Gene expression Gene frequency Gene sequencing Genetic aspects Genetic diversity Genomes Health aspects Heterogeneity Histocompatibility antigen HLA Humans Immune response Immune system Immunology Infectious diseases Influenza Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - immunology Influenza, Human - epidemiology Medicine and Health Sciences Minority & ethnic groups Outbreaks Pandemics People and Places Population Population genetics Population studies Populations Software Supervision Swine flu Tracks (paths) Trends United Kingdom > UK India
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