Regional asymmetry of metabolic and antioxidant profile in the sciaenid fish shi drum (Umbrina cirrosa) white muscle. Response to starvation and refeeding

• Published in: Redox biology Vol. 11; pp. 682 - 687
• Main Authors: Hidalgo, M. Carmen, Morales, Amalia E., Arizcun, Marta, Abellán, Emilia, Cardenete, Gabriel
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-04-2017; Elsevier
• Subjects: Animals; Antioxidants - metabolism; Fishes - metabolism; Lipid Peroxidation - genetics; Liver - metabolism; Metabolic and antioxidant response; Muscle, Skeletal - metabolism; Oxidative Stress; Refeeding; Research Paper; Shi drum; Starvation; White muscle; Starvation; Shi drum; Metabolic and antioxidant response; Refeeding; White muscle
• ISSN: 2213-2317; 2213-2317
• DOI: 10.1016/j.redox.2017.01.022

The objective of the present study is to characterize the metabolic and antioxidant profile of white muscle of shi drum in two sites of the body, anterior dorsal (AM) and posterior dorsal (PM) portions. In addition, it will be analyzed the possible effect of starvation and a subsequent refeeding, with two different protocols, pair feeding and ad libitum. Activities of key enzymes of intermediary metabolism and of antioxidant enzymes, as well as lipid peroxidation, as an index of oxidative stress, were evaluated. The results indicate the existence of a regional asymmetry of the metabolic capacities of the white muscle of shi drum, which is likely related to the different contribution to swimming of the body regions examined. Starvation induces a metabolic depression that is more marked in those activities that support burst swimming in PM, while those activities supporting maintenance requirements are conserved. The greatest energy demands during starvation appear to lie in AM, which showed the highest oxidative metabolism rate. The increased use of fatty acids as energy source for AM leads to oxidative stress. A period of more than four weeks of refeeding for full restoration of metabolic capacities in AM is needed, probably related to the higher muscle mass located in this region. On the contrary, all enzyme activities in PM returned to control levels in both refeeding protocols, but pair feeding seems to be advantageous since compensatory growth has been taking place without signs of oxidative stress. This work was addressed to gain knowledge on the physiology of a promising fish species in aquaculture like shi drum. The results displayed here show how the starving and further re-feeding events could generate oxidative stress situations characterized by high lipid peroxidation levels which may influence negatively on the quality of the edible part of the fish. This study opens an interesting field on this fish species which deserves being investigated in the future.
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•Research on the metabolism of a new fish species with potential aquaculture practices is depicted.•Starving and refeeding promote different metabolic alterations depending on body region of white muscle.•Fasting and refeeding may influence the quality of the edible part of the fish.