Paracoccidioidal Infection in HIV Patients at an Endemic Area of Paracoccidioidomycosis in Brazil

• Published in: Mycopathologia (1975) Vol. 173; no. 2-3; pp. 145 - 149
• Main Authors: Sarti, Elaine Cristina Fernandes Baez, de Oliveira, Sandra Maria do Valle Leone, dos Santos, Liara Ferreira, de Camargo, Zoilo Pires, Paniago, Anamaria Mello Miranda
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01-03-2012; Springer; Springer Nature B.V
• Subjects: Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome - complications; Adult; AIDS; AIDS (Disease); Biomedical and Life Sciences; Brazil - epidemiology; Comorbidity; Cross-Sectional Studies; Disease; Endemic Diseases; Eukaryotic Microbiology; Female; Glycoproteins; HIV; HIV (Viruses); HIV patients; HIV testing; Human immunodeficiency virus; Humans; Infection; Infections; Life Sciences; Male; Medical Microbiology; Microbial Ecology; Microbiology; Middle Aged; Mycoses; Paracoccidioides - genetics; Paracoccidioides - isolation & purification; Paracoccidioidomycosis - epidemiology; Paracoccidioidomycosis - etiology; Paracoccidioidomycosis - microbiology; Plant Sciences; Pneumonia; Prevalence; Prevalence studies (Epidemiology); Serology; Young Adult; Brazil; Epidemiological survey; HIV; Skin test
• ISSN: 0301-486X; 1573-0832
• DOI: 10.1007/s11046-011-9495-6

The association between paracoccidioidomycosis (PCM) and AIDS is relatively rare in contrast to the higher incidence of other systemic mycosis. The explanation may be that AIDS is still predominantly an urban disease, and the PCM is endemic in Latin American rural areas. The aim of this study was to detect the prevalence of
Paracoccidioides brasiliensis
infection in HIV-positive patients at an endemic area of paracoccidioidomycosis in Brazil. Skin test with purified 43 kD glycoprotein (gp43) was performed in 90 HIV/AIDS patients. The prevalence found was 12.2% and it may be even greater, considering that HIV/AIDS patients may not respond to the intradermal test, which depends on cellular immunity for its positivity.