Genetic events in the pathogenesis of multiple myeloma

The genetics of myeloma has been increasingly elucidated in recent years. Recurrent genetic events, and also biologically distinct and clinically relevant genetic subtypes of myeloma have been defined. This has facilitated our understanding of the molecular pathogenesis of the disease. In addition,...

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Bibliographic Details
Published in:	Best practice & research. Clinical haematology Vol. 20; no. 4; pp. 571 - 596
Main Authors:	Chng, W.J., MD, Glebov, O., PhD, Bergsagel, P.L., MD, Kuehl, W.M., MD
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-12-2007
Subjects:	Gene Expression Profiling genetics Hematology, Oncology and Palliative Medicine Humans hyperdiploid IgH translocations Immunoglobulin Heavy Chains - genetics Immunoglobulin Light Chains - genetics Karyotyping molecular pathogenesis Multiple Myeloma - classification Multiple Myeloma - genetics Multiple Myeloma - physiopathology NF-kappa B - metabolism Prognosis Translocation, Genetic IgH translocations genetics gene expression profiling prognosis molecular pathogenesis hyperdiploid
Online Access:	Get full text
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