Perfluorinated chemicals in blood serum of inhabitants in central Poland in relation to gender and age

• Published in: The Science of the total environment Vol. 532; pp. 548 - 555
• Main Authors: Góralczyk, Katarzyna, Pachocki, Krzysztof A., Hernik, Agnieszka, Struciński, Paweł, Czaja, Katarzyna, Lindh, Christian H., Jönsson, Bo A.G., Lenters, Virissa, Korcz, Wojciech, Minorczyk, Maria, Matuszak, Małgorzata, Ludwicki, Jan K.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-11-2015
• Subjects: Adult; Age; Alkanesulfonic Acids - blood; Arbetsmedicin och miljömedicin; Blood; Caprylates - blood; Decanoic Acids - blood; Environmental Exposure - analysis; Environmental Exposure - statistics & numerical data; Environmental Health and Occupational Health; Environmental Pollutants - blood; Female; Fluorocarbons - blood; Health Sciences; Human; Humans; Hälsovetenskap; Inhabitants; Lauric Acids - blood; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Men; Middle Aged; PFASs; PFOA; PFOS; Poland; POPs; Samples; Serum; Serum levels; Serums; Sulfonic acid; Young Adult; Poland; Serum levels; PFASs; PFOA; POPs; PFOS
• ISSN: 0048-9697; 1879-1026; 1879-1026
• DOI: 10.1016/j.scitotenv.2015.06.050

The goal of this paper is to determine concentrations of seven selected perfluoroalkylated substances (PFASs): perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorododecanoic acid (PFDoDA) in the blood serum of men and women of reproductive age from the central region of Poland. The relation between sex of tested subjects and the levels of compounds in blood serum of humans will also be considered and analysed as an element of the risk assessment. The study was made on the blood serum samples collected from 253 women and 176 men of reproductive age between 20 and 44years from Warsaw and surrounding areas. Higher concentrations of five (PFOS, PFOA, PFNA, PFDA, PFUnDA) from among seven selected PFASs were observed in men in comparison to women from the same populations. Only the concentrations of PFHxS and PFDoDA were slightly higher in women than in men. These differences were statistically significant in all cases, except for PFUnDA. The hypothesis that the concentrations of said compounds increase with age of the test subjects, regardless of gender has not been confirmed.
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•Concentrations of seven selected PFASs in serum samples of men and women were analysed.•Higher concentrations were observed in five of seven PFASs in men than women.•PFHxS and PFDoDA were statistically insignificant higher in women than in men.•Hypothesis that concentrations of PFASs increase with age, regardless of sex, was not confirmed.