Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections

Background Antimicrobial resistance (AMR) is rising at an alarming rate and complicating the management of infectious diseases including lower respiratory tract infections (LRTI). Metagenomic next-generation sequencing (mNGS) is a recently established method for culture-independent LRTI diagnosis, b...

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Bibliographic Details
Published in:	Genome medicine Vol. 14; no. 1; pp. 1 - 74
Main Authors:	Serpa, Paula Hayakawa, Deng, Xianding, Abdelghany, Mazin, Crawford, Emily, Malcolm, Katherine, Caldera, Saharai, Fung, Monica, McGeever, Aaron, Kalantar, Katrina L, Lyden, Amy, Ghale, Rajani, Deiss, Thomas, Neff, Norma, Miller, Steven A, Doernberg, Sarah B, Chiu, Charles Y, DeRisi, Joseph L, Calfee, Carolyn S, Langelier, Charles R
Format:	Journal Article
Language:	English
Published:	London BioMed Central Ltd 12-07-2022 BioMed Central BMC
Subjects:	Acute respiratory distress syndrome Antibiotics Antimicrobial agents Antimicrobial resistance Biotechnology industry CRISPR Deoxyribonucleic acid Diseases DNA DNA sequencing Drug resistance Drug resistance in microorganisms Epidemiology Gene expression Genes Genomes Gram-negative bacteria Gram-positive bacteria Health aspects Infectious diseases Intubation Laboratories Mechanical ventilation Medical research Medicine, Experimental Metagenomics Microbiomes Microbiota Next-generation sequencing Nucleotide sequence Nucleotide sequencing Ontology Pathogens Patients Penicillin Respiratory failure Respiratory tract diseases Respiratory tract infection RNA Staphylococcus infections Streptococcus infections Taxonomy United Kingdom United States United States United Kingdom
Online Access:	Get full text
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