Ex Vivo Major Histocompatibility Complex I Knockdown Prolongs Rejection-free Allograft Survival

BACKGROUND:Widespread application of vascularized composite allotransplantation (VCA) is currently limited by the required lifelong systemic immunosuppression and its associated morbidity and mortality. This study evaluated the efficacy of ex vivo (after procurement but before transplantation) engin...

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Bibliographic Details

Published in:	Plastic and reconstructive surgery. Global open Vol. 6; no. 6; p. e1825
Main Authors:	Chang, Jessica B., Rifkin, William J., Soares, Marc A., Duckworth, April, Rao, Nakul, Low, Yee Cheng, Massie, Jonathan P., Rabbani, Piul S., Saadeh, Pierre B., Ceradini, Daniel J.
Format:	Journal Article
Language:	English
Published:	United States The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons 01-06-2018 Copyright The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Plastic Surgeons. All rights reserved Wolters Kluwer Health Wolters Kluwer
Subjects:	Experimental
Online Access:	Get full text
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