The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons

The aim of the current study was to investigate the effect of macrophage polarization on the expression of oxytocin (OT) and the oxytocin receptor (OTR) in enteric neurons. In this study, we used a classic colitis model and D-mannose model to observe the correlation between macrophage polarization a...

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Bibliographic Details
Published in:	Journal of neuroinflammation Vol. 18; no. 1; p. 261
Main Authors:	Shi, Yao, Li, Shuang, Zhang, Haojie, Zhu, Jianchun, Che, Tongtong, Yan, Bing, Li, Jingxin, Liu, Chuanyong
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 08-11-2021 BioMed Central BMC
Subjects:	Alcohol Animals Antibodies Cell Differentiation - immunology Colitis Colitis - immunology Colitis - metabolism Colon Enteric nervous system Enteric Nervous System - immunology Enteric Nervous System - metabolism Heat IL-1β Inflammation Inflammatory bowel disease Interleukin 4 Interleukin 6 Intestines Laboratory animals Lipopolysaccharides Macrophage polarization Macrophages Macrophages - immunology Mannose Mesentery Mice Mice, Inbred C57BL Neural-immune interactions Neurons Neurons - immunology Neurons - metabolism NF-κB protein OT signalling system Oxytocin Oxytocin - immunology Oxytocin - metabolism Peg3 protein Physiological aspects Polarization Proinflammatory and anti-inflammatory factors Proteins Receptors, Oxytocin - immunology Receptors, Oxytocin - metabolism Signal transduction Signal Transduction - immunology Smad2 protein Stat3 protein Tumor necrosis factor-α China Beijing China United States > US Japan Macrophage polarization OT signalling system Neural-immune interactions Proinflammatory and anti-inflammatory factors
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