Determination of inulin clearance by bolus intravenous injection in healthy subjects and ascitic patients: equivalence of systemic and renal clearances as glomerular filtration markers

Aims Determination of systemic inulin clearance by the standard technique of constant intravenous infusion has long been accepted as a reliable method for measuring glomerular filtration rate (GFR) without urine collection, except in oedematous patients. However, recent studies using standard cleara...

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Bibliographic Details
Published in:	British journal of clinical pharmacology Vol. 46; no. 6; pp. 605 - 609
Main Authors:	ORLANDO, R, FLOREANI, M, PADRINI, R, PALATINI, P
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science Ltd 01-12-1998 Blackwell Science Blackwell Science Inc
Subjects:	Ascites - metabolism Biological and medical sciences bolus i.v. injection Glomerular Filtration Rate Humans Injections, Intravenous Inulin - administration & dosage Inulin - blood Inulin - pharmacokinetics inulin clearance Investigative techniques, diagnostic techniques (general aspects) Kidney - drug effects Kidney - metabolism kinetic analysis Liver Cirrhosis - metabolism Male Medical sciences Metabolic Clearance Rate Middle Aged Original Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Urinary system Human Urine Biological fluid Plasma Glomerular filtration Intravenous administration Effusion Clearance Case control study Biological monitoring Investigation method Abdominal disease Inulin Ascites Pharmacokinetics
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