Hepatoprotective effects of Tagetes lucida root extract in carbon tetrachloride-induced hepatotoxicity in Wistar albino rats through amelioration of oxidative stress

The roots of Tagetes lucida Cav. (Asteraceae) have antioxidant and antimicrobial properties. This study aimed to examine the hepatoprotective effects of T. lucida roots ethanol extract (TLRE) using carbon tetrachloride (CCl 4 )-induced hepatotoxicity in rats. The active ingredients of TLRE were iden...

Full description

Saved in:

Bibliographic Details
Published in:	Pharmaceutical biology Vol. 59; no. 1; pp. 984 - 995
Main Authors:	El-Newary, Samah Ali, Ismail, Rasha Fouad, Shaffie, Nermeen Mohammed, Hendawy, Saber Fayez, Omer, Elsayed, Ahmed, Mahgoub Mohammed, ELsayed, Wael M.
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 01-01-2021 Taylor & Francis Ltd Taylor & Francis Group
Subjects:	Alanine Alanine transaminase Alanine Transaminase - blood Alkaline phosphatase Animals Anti-inflammatory effect antioxidant characteristics Antioxidants Aspartate aminotransferase Aspartate Aminotransferases - blood Carbon Carbon tetrachloride Carbon Tetrachloride - pharmacokinetics Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - pathology Chromatography Clinical trials CYP2E1 inhibitor Cytochrome Cytochrome P-450 CYP2E1 - metabolism Cytochrome P450 Drug dosages Enzymes Ethanol Flavonoids Force-feeding Hepatotoxicity High-performance liquid chromatography Lipid peroxidation Lipids Lipids - blood Liver - pathology Male Metabolites Models, Animal Oral administration Oxidative stress Oxidative Stress - drug effects Plant Extracts - pharmacology Rats Rats, Wistar Research centers Seeds Silymarin Silymarin - pharmacology Tagetes - chemistry Tagetes lucida Toxicity Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-α Tumors CYP2E1 inhibitor Anti-inflammatory effect antioxidant characteristics
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!