Rutin Inhibits Oleic Acid Induced Lipid Accumulation via Reducing Lipogenesis and Oxidative Stress in Hepatocarcinoma Cells

: Excessive lipid accumulation within liver has been proposed to cause obesity, hyperlipidemia, diabetes, and fatty liver disease. Rutin, a common dietary flavonoid that is consumed in fruits, vegetables, and plant‐derived beverages, has various biological functions, including antioxidant, anti‐inf...

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Bibliographic Details
Published in:	Journal of food science Vol. 76; no. 2; pp. T65 - T72
Main Authors:	Wu, Cheng-Hsun, Lin, Ming-Cheng, Wang, Hsueh-Chun, Yang, Mon-Yuan, Jou, Ming-Jia, Wang, Chau-Jong
Format:	Journal Article
Language:	English
Published:	Malden, USA Blackwell Publishing Inc 01-03-2011 Wiley Wiley Subscription Services, Inc
Subjects:	Acyl Coenzyme A - metabolism AMP-Activated Protein Kinases - metabolism antioxidant enzymes Antioxidants Biological and medical sciences Blotting, Western Cells Effects Fatty Acid Synthases - metabolism Food industries Food science Fundamental and applied biological sciences. Psychology Gene Expression Glycerol-3-Phosphate O-Acyltransferase - metabolism Hep G2 Cells hepatic lipogenesis Hepatocytes - metabolism Humans Hypolipidemic Agents - pharmacology Kinases lipid accumulation Lipids Lipids - biosynthesis Lipogenesis - drug effects Liver - cytology Liver - metabolism Molecules Oleic Acid - metabolism Oxazines Oxidative Stress - drug effects Peroxisome Proliferator-Activated Receptors Reverse Transcriptase Polymerase Chain Reaction rutin Rutin - pharmacology Sterol Regulatory Element Binding Protein 1 - metabolism Studies Oxidative stress Oleic acid Enzyme Monounsaturated fatty acid Lipids antioxidant enzymes hepatic lipogenesis rutin Antioxidant lipid accumulation
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