Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

• Published in: The New England journal of medicine Vol. 384; no. 24; pp. 2273 - 2282
• Main Authors: Shimabukuro, Tom T, Kim, Shin Y, Myers, Tanya R, Moro, Pedro L, Oduyebo, Titilope, Panagiotakopoulos, Lakshmi, Marquez, Paige L, Olson, Christine K, Liu, Ruiling, Chang, Karen T, Ellington, Sascha R, Burkel, Veronica K, Smoots, Ashley N, Green, Caitlin J, Licata, Charles, Zhang, Bicheng C, Alimchandani, Meghna, Mba-Jonas, Adamma, Martin, Stacey W, Gee, Julianne M, Meaney-Delman, Dana M
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 17-06-2021
• Subjects: Abortion, Spontaneous - epidemiology; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Adverse events; Coronaviruses; COVID-19; COVID-19 vaccines; COVID-19 Vaccines - adverse effects; COVID-19 Vaccines - immunology; Female; Fever; Gestational age; Humans; Immunization; Infant, Newborn; Infant, Small for Gestational Age; Middle Aged; Miscarriage; mRNA; mRNA Vaccines; Myalgia; Neonates; Original; Pandemics; Pregnancy; Premature birth; Premature Birth - epidemiology; Public Health Surveillance - methods; Registries; Safety; United States - epidemiology; Vaccines; Vaccines, Synthetic - adverse effects; Womens health; Young Adult; United States; United States > US
• ISSN: 0028-4793; 1533-4406
• DOI: 10.1056/NEJMoa2104983

Preliminary data from the CDC “v-safe after vaccination health checker” surveillance system, the v-safe pregnancy registry, and the Vaccine Adverse Event Reporting System did not show any obvious safety signals among pregnant persons who received mRNA Covid-19 vaccines. More data are needed to better inform maternal, pregnancy, and infant outcomes.