Evaluation of invasive breast cancer samples using a 12-chemokine gene expression score: correlation with clinical outcomes

A unique 12-chemokine gene expression score (CS) accurately predicted the presence of tumor-localized, ectopic lymph node-like structures (TL-ELNs) and improved overall survival (OS) in primary colorectal cancer and metastatic melanoma. We analyzed the correlation between CS, clinicopathological var...

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Bibliographic Details
Published in:	Breast cancer research : BCR Vol. 19; no. 1; p. 71
Main Authors:	Prabhakaran, Sangeetha, Rizk, Victoria T, Ma, Zhenjun, Cheng, Chia-Ho, Berglund, Anders E, Coppola, Dominico, Khalil, Farah, Mulé, James J, Soliman, Hatem H
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 19-06-2017 BioMed Central BMC
Subjects:	Adult Aged Aged, 80 and over Biomarkers, Tumor Breast cancer Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - therapy Cancer therapies Cell adhesion & migration Chemokines Chemokines - genetics Clinical outcomes Colorectal carcinoma Development and progression Diabetes ErbB-2 protein Female Follow-Up Studies Gene Expression Gene Expression Profiling Gene expression score Genetic aspects Humans Immunology Immunotherapy Invasiveness Kaplan-Meier Estimate Kinases Lymph Lymph nodes Lymphatic system Lymphocytes Medical prognosis Melanoma Metastases Metastasis Middle Aged Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Outcomes Patients Physiological aspects Predictive marker Principal components analysis Prognosis Survival Survival analysis Tumor Microenvironment - genetics Tumors Young Adult United States United States > US Gene expression score Breast cancer Immunology Chemokines Outcomes Predictive marker
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