Apolipoprotein E and Presenilin-1 Allelic Variation and Alzheimer's Disease in India

As part of a larger epidemiological survey to study the prevalence of dementia in a suburb of Mumbai, Western India, we identified 78 cases with a Clinical Dementia Rating (CDR) ≥ 1.0. Of these, 49 Alzheimer's disease (AD) cases were analyzed for risk association with APOE E*4 allele at apolipo...

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Bibliographic Details
Published in:	Human biology Vol. 74; no. 5; pp. 683 - 693
Main Authors:	CHANDAK, G.R., SRIDEVI, M. UMA, VAS, C.J., PANIKKER, D.M., SINGH, L.
Format:	Journal Article
Language:	English
Published:	United States Wayne State University Press 01-10-2002
Subjects:	Aged Aged, 80 and over Alleles Alzheimer Disease - diagnosis Alzheimer Disease - epidemiology Alzheimer Disease - genetics Alzheimer's disease Alzheimers disease Amyloids Apolipoprotein E4 Apolipoproteins Apolipoproteins E - genetics Case-Control Studies Causes of Degeneration Dementia Epidemiology Gene frequency Genes Genetic aspects Genetic Testing Genetic Variation - genetics Genetics Genetics, Population Genotype Genotypes Humans India - epidemiology Introns - genetics Medical genetics Membrane Proteins - genetics Mental Status Schedule Middle Aged Nerve degeneration Nervous system Neurodegenerative diseases Polymorphism, Genetic - genetics Population genetics Predisposing factors Presenilin-1 Prevalence Risk Factors Statistics Vascular dementia India
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