Dynamic response of microglia/macrophage polarization following demyelination in mice

The glial response in multiple sclerosis (MS), especially for recruitment and differentiation of oligodendrocyte progenitor cells (OPCs), predicts the success of remyelination of MS plaques and return of function. As a central player in neuroinflammation, activation and polarization of microglia/mac...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of neuroinflammation Vol. 16; no. 1; pp. 188 - 22
Main Authors:	Chu, Tianci, Zhang, Yi Ping, Tian, Zhisen, Ye, Chuyuan, Zhu, Mingming, Shields, Lisa B E, Kong, Maiying, Barnes, Gregory N, Shields, Christopher B, Cai, Jun
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 17-10-2019 BioMed Central BMC
Subjects:	Animals Antigen presentation Astrocytes Brain research Cell activation Cell differentiation Cytokines Demyelinating Diseases - diagnostic imaging Demyelinating Diseases - metabolism Demyelination Female Focal demyelination model Genetic aspects Glial stem cells Hand Strength - physiology Inflammation Lesions Lipopolysaccharides Macrophages Macrophages - metabolism Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical examination Mice Mice, Inbred C57BL Microglia Microglia - metabolism Microglia/macrophage Multiple sclerosis Myelination Neuroinflammation Neuronal-glial interactions Observations Oligodendrocyte/oligodendrocyte progenitor cells Oligodendrocytes Phenotypes Plaques Polarization Progenitor cells Sensorimotor function Sensorimotor system Surgery Temporal variations United States Sensorimotor function Multiple sclerosis Neuroinflammation Microglia/macrophage Oligodendrocyte/oligodendrocyte progenitor cells Focal demyelination model Diffusion tensor imaging
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!