Identifying placebo responders and predictors of response in osteoarthritis: a protocol for individual patient data meta-analysis

The management of osteoarthritis (OA) is unsatisfactory, as most treatments are not clinically effective over placebo and most drugs have considerable side effects. On average, 75 % of the analgesic effect from OA treatments in clinical trials can be attributed to a placebo response, and this respon...

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Bibliographic Details

Published in:	Systematic reviews Vol. 5; no. 1; pp. 183 - 6
Main Authors:	Fu, Yu, Persson, Monica S M, Bhattacharya, Archan, Goh, Siew-Li, Stocks, Joanne, van Middelkoop, Marienke, Bierma-Zeinstra, Sita M A, Walsh, David, Doherty, Michael, Zhang, Weiya
Format:	Journal Article
Language:	English
Published:	England BioMed Central 28-10-2016 BMC
Subjects:	Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis Humans Individual patient data meta-analysis Meta-analysis Osteoarthritis Osteoarthritis, Knee - drug therapy Placebo Effect Placebo response Protocol Randomized Controlled Trials as Topic Systematic review Individual patient data meta-analysis Osteoarthritis Placebo response
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