Microfluidic Synthesis of Scalable Layer-by-Layer Multiple Antigen Nano-Delivery Platform for SARS-CoV-2 Vaccines

The COVID-19 outbreak was a global pandemic with wide-ranging healthcare implications. Although several mRNA-based vaccines delivered using lipid nanoparticles (LNP) have been approved and demonstrated efficacy at reducing the severity and spread of infection, continued rapid viral evolution and dis...

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Bibliographic Details
Published in:	Vaccines (Basel) Vol. 12; no. 3; p. 339
Main Authors:	Xu, Yang, Masuda, Kazuya, Groso, Christine, Hassan, Rick, Zhou, Ziyou, Broderick, Kelsey, Tsuji, Moriya, Tison, Christopher
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01-03-2024 MDPI
Subjects:	adjuvant Antibodies Antigens Biocompatibility Chitosan chitosan nanoparticle COVID-19 COVID-19 vaccines Cytokines Drug delivery systems Drugs Evaluation Health aspects layer-by-layer (LbL) Lipids Materials Microfluidics mRNA Nanomedicine Nanoparticles Outbreaks Pandemics Peptides Proteins Ratios SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 sustained releases T-cells Toxicity Vaccines Vehicles Viral diseases United States United States > US T-cells layer-by-layer (LbL) SARS-CoV-2 chitosan nanoparticle sustained releases adjuvant
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