Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up‐regulated upon dendritic cell maturation

The lone CX3C chemokine, fractalkine (FK), is expressed in a membrane‐bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. We now show that FK is associated with dendritic cells (DC) in epidermis and lymphoid organs. In normal human...

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Bibliographic Details
Published in:	European journal of immunology Vol. 29; no. 8; pp. 2551 - 2559
Main Authors:	Papadopoulos, Elektra J., Sassetti, Chris, Saeki, Hidehisa, Yamada, Nobuo, Kawamura, Tatsuyoshi, Fitzhugh, David J., Saraf, Manisha A., Schall, Thomas, Blauvelt, Andrew, Rosen, Steven D., Hwang, Sam T.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY‐VCH Verlag GmbH 01-08-1999
Subjects:	Animals Base Sequence CD40 Ligand Cell Adhesion - immunology Cell Communication - immunology Cell Differentiation - immunology Cell Line Chemokine chemokine CX3C Chemokine CX3CL1 Chemokines, CX3C Chemokines, CXC - genetics Chemokines, CXC - metabolism Dendritic cell Dendritic Cells - cytology Dendritic Cells - immunology DNA Primers - genetics fractalkine Humans Langerhans Cells - immunology Melanocytes - immunology Membrane Glycoproteins - pharmacology Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Inbred BALB C Palatine Tonsil - cytology Palatine Tonsil - immunology RNA, Messenger - genetics RNA, Messenger - metabolism Skin Skin - cytology Skin - immunology T-Lymphocytes - cytology T-Lymphocytes - immunology Tumor Necrosis Factor-alpha - pharmacology Up-Regulation
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