Maternal Effect for DNA Mismatch Repair in the Mouse

DNA mismatch repair (DMR) functions to maintain genome stability. Prokaryotic and eukaryotic cells deficient in DMR show a microsatellite instability (MSI) phenotype characterized by repeat length alterations at microsatellite sequences. Mice deficient in Pms2, a mammalian homolog of bacterial mutL,...

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Bibliographic Details
Published in:	Genetics (Austin) Vol. 160; no. 1; pp. 271 - 277
Main Authors:	Gurtu, Vanessa E, Verma, Shelly, Grossmann, Allie H, Liskay, R. Michael, Skarnes, William C, Baker, Sean M
Format:	Journal Article
Language:	English
Published:	United States Genetics Soc America 01-01-2002 Genetics Society of America
Subjects:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - physiology Animals Base Pair Mismatch Crosses, Genetic Deoxyribonucleic acid DNA DNA Repair DNA Repair Enzymes DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Female Genetics Male Mice Mice, Inbred C57BL Microsatellite Repeats mismatch repair Mismatch Repair Endonuclease PMS2 Mosaicism - genetics Mutation mutL gene Pms2 gene Rodents
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