Role for FGFR2IIIb-Mediated Signals in Controlling Pancreatic Endocrine Progenitor Cell Proliferation

Pancreatic development is a classic example of epithelium-mesenchyme interaction. During embryonic life, signals from the mesenchyme control the proliferation of precursor cells within the pancreatic epithelium and their differentiation into endocrine or acinar cells. It has been shown that signals...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 99; no. 6; pp. 3884 - 3889
Main Authors:	Elghazi, Lynda, Cras-Méneur, Corentin, Czernichow, Paul, Scharfmann, Raphael
Format:	Journal Article
Language:	English
Published:	United States National Academy of Sciences 19-03-2002 National Acad Sciences The National Academy of Sciences
Subjects:	Acinar cells Animals Biological Sciences Biomarkers - analysis Cell Differentiation - drug effects Cell Division - drug effects Cells Cellular differentiation Developmental biology Endocrine cells Enzymes Epithelial cells Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - metabolism Epithelium Fibroblast Growth Factor 7 Fibroblast Growth Factors - pharmacology Flavonoids - pharmacology Insulin Insulin - metabolism Keratins - metabolism MAP Kinase Signaling System - drug effects Mesenchymal stem cells Morphogenesis - drug effects Pancreas Pancreas - cytology Pancreas - drug effects Pancreas - embryology Pancreas - metabolism Pancreatic cells Progenitor cells Proteins Rats Receptor Protein-Tyrosine Kinases - metabolism Receptor, Fibroblast Growth Factor, Type 2 Receptors, Fibroblast Growth Factor - genetics Receptors, Fibroblast Growth Factor - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Stem Cells - cytology Stem Cells - drug effects Stem Cells - metabolism
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