Role of oxygen radicals in DNA damage and cancer incidence

The development of cancer in humans and animals is a multistep process. The complex series of cellular and molecular changes participating in cancer development are mediated by a diversity of endogenous and exogenous stimuli. One type of endogenous damage is that arising from intermediates of oxygen...

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Bibliographic Details
Published in:	Molecular and cellular biochemistry Vol. 266; no. 1-2; pp. 37 - 56
Main Authors:	Valko, M, Izakovic, M, Mazur, M, Rhodes, C.J, Telser, J
Format:	Journal Article
Language:	English
Published:	Netherlands Springer Nature B.V 01-11-2004
Subjects:	Animals Antioxidants Antioxidants - metabolism ascorbic acid Cancer Carcinogenesis Carotenoids Cell Transformation, Neoplastic - metabolism Deoxyribonucleic acid DNA DNA - metabolism DNA Damage DNA Repair free radicals Free Radicals - metabolism Humans Incidence Lesions Lipid Metabolism Lipids Mutagenesis Mutation neoplasms Neoplasms - epidemiology Neoplasms - metabolism Nutrition Oxidation-Reduction Oxidative Stress Oxidizing agents Oxygen Reactive Oxygen Species - metabolism Selenium vitamin E
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