Carbazomycins G and H, novel carbazomycin-congeners containing a quinol moiety

Carbazomycins G (I) and H (II), new congeners of the carbazomycin complex, have been isolated from the culture broth of Streptoverticillium ehimense. They have proved to contain a unique quinol moiety in the molecule. Their structures have been elucidated by mass and NMR spectrometries and X-ray cry...

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Bibliographic Details
Published in:	Journal of antibiotics Vol. 41; no. 5; p. 602
Main Authors:	Kaneda, M, Naid, T, Kitahara, T, Nakamura, S, Hirata, T, Suga, T
Format:	Journal Article
Language:	English
Published:	Japan 1988
Subjects:	Anti-Bacterial Agents - isolation & purification Carbazoles - isolation & purification Carbazoles - pharmacology Chemical Phenomena Chemistry Crystallography Drug Evaluation, Preclinical Hydroquinones - isolation & purification Models, Molecular Spectrum Analysis Streptomycetaceae - analysis X-Ray Diffraction
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Summary:	Carbazomycins G (I) and H (II), new congeners of the carbazomycin complex, have been isolated from the culture broth of Streptoverticillium ehimense. They have proved to contain a unique quinol moiety in the molecule. Their structures have been elucidated by mass and NMR spectrometries and X-ray crystallographic analysis. Carbazomycin G showed moderate antifungal activity against Trichophyton species.
ISSN:	0021-8820
DOI:	10.7164/antibiotics.41.602