Monoclonal antibody to a conserved epitope on proteins encoded by Babesia bigemina and present on the surface of intact infected erythrocytes

To define Babesia bigemina-specific antigens on the surface of infected erythrocytes, monoclonal antibodies (MAbs) were identified by live cell immunofluorescence. As determined by live-cell immunofluorescence, two MAbs made to the Mexico strain reacted with the Mexico strain and three Kenya strains...

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Bibliographic Details
Published in:	Infection and Immunity Vol. 63; no. 9; pp. 3507 - 3513
Main Authors:	Shompole, S. (Kenya Agricultural Research Institute, Kabete, Kenya.), Perryman, L.E, Rurangirwa, F.R, McElwain, T.F, Jasmer, D.P, Musoke, A.J, Wells, C.W, McGuire, T.C
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-09-1995
Subjects:	Animals Antibodies, Monoclonal - immunology Antibodies, Protozoan - biosynthesis Antibodies, Protozoan - immunology ANTICORPS MONOCLONAL ANTICUERPOS MONOCLONALES ANTIGENE ANTIGENOS Antigens, Protozoan - analysis Antigens, Surface - analysis Applied microbiology Babesia - immunology BABESIA BIGEMINA Biological and medical sciences BOVIN Cattle DIFERENCIAS BIOLOGICAS DIFFERENCE BIOLOGIQUE Epitopes ERITROCITOS ERYTHROCYTE Erythrocytes - parasitology ETAPAS DE DESARROLLO FAGOCITOS Fundamental and applied biological sciences. Psychology GANADO BOVINO Immunoblotting INFECCIONES POR PROTOZOOS Mice Mice, Inbred BALB C Microbiology Microscopy, Immunoelectron MONOCITOS MONOCYTE PHAGOCYTE Phagocytosis PROTOZOOSE STADE DE DEVELOPPEMENT Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Protozoa Bovine Antigenic determinant Red blood cell Monoclonal antibody Cell surface Antigen Babesia bigemina Blood cell Vertebrata Conserved sequence Mammalia Antigenicity Immunogenicity Artiodactyla Infected cell Sporozoa Ungulata
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