Takayasu arteritis: a review

Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses, classification, and immunology of the disorder. Suppression of inflammation and preservation of vascular competence are the aims of treatment. As w...

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Published in:Journal of clinical pathology Vol. 55; no. 7; pp. 481 - 486
Main Authors: Johnston, S L, Lock, R J, Gompels, M M
Format: Journal Article
Language:English
Published: London BMJ Publishing Group Ltd and Association of Clinical Pathologists 01-07-2002
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Copyright 2002 Journal of Clinical Pathology
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Abstract Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses, classification, and immunology of the disorder. Suppression of inflammation and preservation of vascular competence are the aims of treatment. As with any rare disease, randomised controlled treatment trials are either lacking or based on small patient numbers, making management decisions difficult. Current evidence based treatments are presented and discussed.
AbstractList Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses, classification, and immunology of the disorder. Suppression of inflammation and preservation of vascular competence are the aims of treatment. As with any rare disease, randomised controlled treatment trials are either lacking or based on small patient numbers, making management decisions difficult. Current evidence based treatments are presented and discussed.
Audience Professional
Academic
Author Johnston, S L
Gompels, M M
Lock, R J
AuthorAffiliation Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
AuthorAffiliation_xml – name: Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
Author_xml – sequence: 1
  givenname: S L
  surname: Johnston
  fullname: Johnston, S L
  organization: Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
– sequence: 2
  givenname: R J
  surname: Lock
  fullname: Lock, R J
  organization: Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
– sequence: 3
  givenname: M M
  surname: Gompels
  fullname: Gompels, M M
  organization: Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
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Issue 7
Keywords Human
Pathogenesis
Cardiovascular disease
Review
Differential diagnostic
Vascular disease
Pathology
Symptomatology
Vasculitis
Immunology
Treatment
Systemic disease
Clinical investigation
Diagnosis
Bibliographic review
Takayashu arteritis
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 Dr S L Johnston, Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK;
 sljoh@hotmail.com
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Correspondence to: …Dr S L Johnston, Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK; …sljoh@hotmail.com
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PublicationTitle Journal of clinical pathology
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Snippet Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses,...
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SubjectTerms Abdomen
Abnormalities
ACR
Age
American College of Rheumatology
Aneurysms
Aorta
arteritis
Biological and medical sciences
Blood pressure
C reactive protein
Carotid arteries
Coronary vessels
CRP
Diagnosis, Differential
Dyspnea
erythrocyte sedimentation rate
ESR
Females
HLA
human leucocyte antigen
Humans
Hypertension
Inflammation
interleukin
Ischemia
magnetic resonance angiography
Medical imaging
Medical sciences
MRA
pathogensis
Pulmonary arteries
Review
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Syphilis
Takayasu
Takayasu Arteritis - diagnosis
Takayasu Arteritis - drug therapy
Takayasu Arteritis - immunology
Takayasu's arteritis
treatment
Tuberculosis
Vein & artery diseases
Title Takayasu arteritis: a review
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