Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization

Microarray profiling of gene expression is a powerful tool for discovery, but the ability to manage and compare the resulting data can be problematic. Biological, experimental, and technical variations between studies of the same phenotype/phenomena create substantial differences in results. The app...

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Bibliographic Details
Published in:	Gene Vol. 401; no. 1; pp. 12 - 18
Main Authors:	Cahan, Patrick, Rovegno, Felicia, Mooney, Denise, Newman, John C., St. Laurent, Georges, McCaffrey, Timothy A.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15-10-2007
Subjects:	Aging Animals Bioinformatics Computational Biology Data Interpretation, Statistical Databases, Genetic Expression profiling Gene annotation Gene expression Gene Expression Profiling Gene Expression Regulation Humans Meta-analysis Meta-Analysis as Topic Microarray Oligonucleotide Array Sequence Analysis - standards Species Specificity Transcript profiling AML NPC MIAME Expression profiling RPC Transcript profiling SAGE Microarray Gene expression Meta-analysis IFN DEGs ESC Aging ApoD LOLA SMART Bioinformatics Gene annotation
Online Access:	Get full text
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