Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

There is little axonal growth after central nervous system (CNS) injury in adult mammals. The administration of antibodies (IN-1) to neutralize the myelin-associated neurite growth inhibitory proteins leads to long-distance regrowth of a proportion of CNS axons after injury. Our aim was: to determin...

Full description

Saved in:

Bibliographic Details
Published in:	Nature (London) Vol. 378; no. 6556; pp. 498 - 501
Main Authors:	Bregman, Barbara S, Kunkel-Bagden, Ellen, Schnell, Lisa, Dai, Hai Ning, Gao, Da, Schwab, Martin E
Format:	Journal Article
Language:	English
Published:	London Nature Publishing 30-11-1995 Nature Publishing Group
Subjects:	Animals Axons - physiology Biological and medical sciences Brain Stem - cytology Cell Division Cellular biology Central nervous system Development. Senescence. Regeneration. Transplantation Fundamental and applied biological sciences. Psychology Growth Inhibitors - antagonists & inhibitors Growth Inhibitors - immunology Inhibitors Locomotion Nerve Regeneration Neural Pathways Neuronal Plasticity Plasticity Rats Rats, Inbred Lew Reflex Regrowth Rodents Spinal cord injuries Spinal Injuries - therapy Vertebrates: nervous system and sense organs Growth inhibitor Spinal cord Neurite Rat Antibody Growth Rodentia Central nervous system Regeneration Vertebrata Mammalia Plasticity Lesion
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!