PD-1 induction through TCR activation is partially regulated by endogenous TGF-β

The programmed death 1 （PD-1） pathway is a way of inhibiting T-cell proliferation and cytokine production. This pathway is important for maintaining peripheral tolerance. Different mechanisms and cytokines are involved in this pathway. Herein, we show the contribution of endogenous TGF-β to increasi...

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Bibliographic Details
Published in:	Cellular & molecular immunology Vol. 12; no. 5; pp. 648 - 649
Main Authors:	Rekik, Raja, Belhadj Hmida, Nadia, Ben Hmid, Ahlem, Zamali, Imen, Kammoun, ns, Ben Ahmed, Melika
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-09-2015 Nature Publishing Group Nature Publishing Group/Chinese Society of Immunology
Subjects:	Antibodies Biomedical and Life Sciences Biomedicine Humans Immunology Leukocytes, Mononuclear - metabolism Life Sciences Medical Microbiology Microbiology PD-1 protein Programmed Cell Death 1 Receptor - metabolism Receptors, Antigen, T-Cell - immunology Receptors, Antigen, T-Cell - metabolism Short Communication T cell receptors TCR TGF-β Transforming Growth Factor beta - metabolism T细胞受体 T细胞增殖 Vaccine 内源性活化细胞因子诱导
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